Source:http://linkedlifedata.com/resource/pubmed/id/21350203
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2011-3-29
|
pubmed:abstractText |
Thrombolysis therapy using tissue-type plasminogen activator (t-PA) is occasionally accompanied by harmful outcomes, including intracerebral hemorrhage. We have reported that Stachybotrys microspora triprenyl phenol-7 (SMTP-7), a candidate thrombolytic drug, has excellent therapeutic effect on cerebral infarction in embolic stroke model in mice; however, little is known regarding whether this agent influences cerebrovascular inflammation following thrombolytic reperfusion. The current study aimed to compare the effects of recombinant t-PA (rt-PA) and SMTP-7 on cerebrovascular inflammation.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1524-4628
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
42
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1097-104
|
pubmed:meshHeading |
pubmed-meshheading:21350203-Animals,
pubmed-meshheading:21350203-Benzopyrans,
pubmed-meshheading:21350203-Cell Line, Tumor,
pubmed-meshheading:21350203-Cells, Cultured,
pubmed-meshheading:21350203-Disease Models, Animal,
pubmed-meshheading:21350203-Humans,
pubmed-meshheading:21350203-Infarction, Middle Cerebral Artery,
pubmed-meshheading:21350203-Inflammation,
pubmed-meshheading:21350203-Intracranial Embolism,
pubmed-meshheading:21350203-Lasers,
pubmed-meshheading:21350203-Male,
pubmed-meshheading:21350203-Mice,
pubmed-meshheading:21350203-Pyrrolidinones,
pubmed-meshheading:21350203-Reperfusion Injury,
pubmed-meshheading:21350203-Thrombolytic Therapy,
pubmed-meshheading:21350203-Tissue Plasminogen Activator
|
pubmed:year |
2011
|
pubmed:articleTitle |
Distinct effects of tissue-type plasminogen activator and SMTP-7 on cerebrovascular inflammation following thrombolytic reperfusion.
|
pubmed:affiliation |
Department of Pharmacology, School of Pharmacy, Showa University, 1-5-8 Hatanodai Shinagawa-ku, Tokyo, 142-8555 Japan. taku@pharm.showa-u.ac.jp
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|