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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-4-21
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pubmed:abstractText |
The regeneration of the hematopoietic system in bone marrow after chemotherapy depends on a balance between the quiescence and proliferation of lineage-specific progenitor cells. Even though the vascular network in bone is damaged by cytoablation, the transcriptional control of quiescence in endothelial cells is not well known. In this study, we investigated the role of the transcription factor E74-like factor (ELF4) in the proliferation of endothelial cells in bone marrow.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CDK4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase 4,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/ELF4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Elf4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorouracil,
http://linkedlifedata.com/resource/pubmed/chemical/Myeloablative Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1185-91
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pubmed:dateRevised |
2011-8-1
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pubmed:meshHeading |
pubmed-meshheading:21350194-Animals,
pubmed-meshheading:21350194-Bone Marrow Cells,
pubmed-meshheading:21350194-COS Cells,
pubmed-meshheading:21350194-Cell Aging,
pubmed-meshheading:21350194-Cell Cycle,
pubmed-meshheading:21350194-Cell Proliferation,
pubmed-meshheading:21350194-Cercopithecus aethiops,
pubmed-meshheading:21350194-Cyclin-Dependent Kinase 4,
pubmed-meshheading:21350194-DNA-Binding Proteins,
pubmed-meshheading:21350194-Drug Resistance,
pubmed-meshheading:21350194-Endothelial Cells,
pubmed-meshheading:21350194-Fluorouracil,
pubmed-meshheading:21350194-Humans,
pubmed-meshheading:21350194-Mice,
pubmed-meshheading:21350194-Mice, Inbred C57BL,
pubmed-meshheading:21350194-Mice, Knockout,
pubmed-meshheading:21350194-Myeloablative Agonists,
pubmed-meshheading:21350194-NIH 3T3 Cells,
pubmed-meshheading:21350194-Neovascularization, Physiologic,
pubmed-meshheading:21350194-Promoter Regions, Genetic,
pubmed-meshheading:21350194-RNA Interference,
pubmed-meshheading:21350194-Time Factors,
pubmed-meshheading:21350194-Transcription Factors,
pubmed-meshheading:21350194-Transfection
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pubmed:year |
2011
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pubmed:articleTitle |
The transcription factor E74-like factor controls quiescence of endothelial cells and their resistance to myeloablative treatments in bone marrow.
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pubmed:affiliation |
Department of Pathology and Immunology, Baylor College of Medicine, Texas Children's Hospital, 1102 Bates St, Ste 830, Houston, TX 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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