Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2011-4-25
pubmed:abstractText
Bioassay-guided fractionation of extracts of the brown alga Sporochnus comosus led to the isolation of five new compounds, comosusols A-D (3-6) and comosone A (7). The structures of all isolated compounds were elucidated using standard one- and two-dimensional NMR techniques, as well as comparison with literature values. The cytotoxic activity of all compounds was investigated against a panel of human tumor and mammalian cell lines. These assays found eight of the nine compounds had GI(50) values in the 8-63 ?M range.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1520-6025
pubmed:author
pubmed:issnType
Electronic
pubmed:day
25
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
739-43
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Comosusols A-D and comosone A: cytotoxic compounds from the brown alga Sporochnus comosus.
pubmed:affiliation
Australian Institute of Marine Science, PMB No. 3, Townsville MC, Townsville, 4810, Australia.
pubmed:publicationType
Journal Article