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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-7-27
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pubmed:abstractText |
Tissue eosinophilia is one of the hallmarks of allergic diseases and Th2-type immune responses including asthma. Systemic inflammation caused by adipose tissue in obesity via production of adipokines such as leptin has been attracting attention recently as a contributor to exacerbation of allergic immune reactions. In this study, we examined whether leptin might affect eosinophil chemotactic responses.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0097
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pubmed:author |
pubmed-author:ChiharaJunichiJ,
pubmed-author:ChiharaMamiM,
pubmed-author:ItoWataruW,
pubmed-author:ItogaMasamichiM,
pubmed-author:KamadaRieR,
pubmed-author:KatoHikariH,
pubmed-author:KayabaHiroyukiH,
pubmed-author:KiharaJunkoJ,
pubmed-author:SuzukiTomomiT,
pubmed-author:TakedaMasahideM,
pubmed-author:UekiShigeharuS,
pubmed-author:YamauchiYumikoY
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pubmed:copyrightInfo |
Copyright © 2011 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
155
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
335-44
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pubmed:meshHeading |
pubmed-meshheading:21346363-Chemokine CCL11,
pubmed-meshheading:21346363-Chemotaxis, Leukocyte,
pubmed-meshheading:21346363-Eosinophils,
pubmed-meshheading:21346363-Female,
pubmed-meshheading:21346363-Humans,
pubmed-meshheading:21346363-Leptin,
pubmed-meshheading:21346363-Male,
pubmed-meshheading:21346363-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:21346363-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:21346363-Phosphorylation,
pubmed-meshheading:21346363-Recombinant Proteins,
pubmed-meshheading:21346363-Signal Transduction,
pubmed-meshheading:21346363-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2011
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pubmed:articleTitle |
Leptin has a priming effect on eotaxin-induced human eosinophil chemotaxis.
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pubmed:affiliation |
Department of Infection, Allergy, Clinical Immunology and Laboratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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