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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-4-23
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pubmed:abstractText |
The relationship between red blood cell sorbitol content and diabetic complications (cataract, retinopathy, neuropathy, and nephropathy) was examined in 23 non-insulin-dependent diabetic (NIDD) patients. Sorbitol content was abnormally high in 21 cases out of 23 NIDD patients. Sorbitol content in the non-neuropathy group and neuropathy group was 47.3 +/- 11.9 and 59.6 +/- 23.6 nmol/gHb, respectively. In the non-cataract group and cataract group, it was 49.0 +/- 17.6 and 66.0 +/- 23.5 nmol/gHb, respectively. The contents in the Scott I group and Scott II + III group were 54.9 +/- 20.7 and 58.7 +/- 24.0 nmol/gHb, respectively. Sorbitol content in the non-nephropathy group and nephropathy group was 52.8 +/- 19.8 and 61.1 +/- 21.9 nmol/gHb, respectively. The possibility that glyceraldehyde reductase (GAR) and sorbitol dehydrogenase (SDH) levels in red blood cells are also useful indicators of the presence of diabetic complications is strongly suggested.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/L-Iditol 2-Dehydrogenase,
http://linkedlifedata.com/resource/pubmed/chemical/Sorbitol,
http://linkedlifedata.com/resource/pubmed/chemical/Sugar Alcohol Dehydrogenases,
http://linkedlifedata.com/resource/pubmed/chemical/glyceraldehyde reductase
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pubmed:status |
MEDLINE
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pubmed:issn |
0916-0701
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
230-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2134294-Biological Markers,
pubmed-meshheading:2134294-Cataract,
pubmed-meshheading:2134294-Diabetes Mellitus, Type 2,
pubmed-meshheading:2134294-Diabetic Nephropathies,
pubmed-meshheading:2134294-Diabetic Retinopathy,
pubmed-meshheading:2134294-Erythrocytes,
pubmed-meshheading:2134294-Female,
pubmed-meshheading:2134294-Humans,
pubmed-meshheading:2134294-L-Iditol 2-Dehydrogenase,
pubmed-meshheading:2134294-Male,
pubmed-meshheading:2134294-Sorbitol,
pubmed-meshheading:2134294-Sugar Alcohol Dehydrogenases
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pubmed:year |
1990
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pubmed:articleTitle |
Studies on clinical markers of diabetes mellitus. 6. Red blood cell sorbitol and diabetic complications.
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pubmed:affiliation |
Department of Internal Medicine, Meikai University School of Dentistry, Saitama, Japan.
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pubmed:publicationType |
Journal Article
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