Source:http://linkedlifedata.com/resource/pubmed/id/21342027
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2011-4-12
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pubmed:abstractText |
Enterochromaffin-like (ECL) cells are central in the regulation of acid secretion. G cells release gastrin and activate ECL cell histamine secretion which stimulates parietal cell H(2) receptors initiating acid secretion. It is unclear whether histamine-mediated parietal cell activation is via a vascular or paracrine pathway. To assess this, we utilized immunohistochemistry (IHC) and electron microscopy to examine gastric tissue and used visualization of formalin fixed dispersed gastric cells and glands to investigate and define the anatomical relationship between ECL and parietal cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1502-7708
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
531-7
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pubmed:meshHeading |
pubmed-meshheading:21342027-Animals,
pubmed-meshheading:21342027-Cell Communication,
pubmed-meshheading:21342027-Enterochromaffin-like Cells,
pubmed-meshheading:21342027-Female,
pubmed-meshheading:21342027-Gastric Acid,
pubmed-meshheading:21342027-Gastric Mucosa,
pubmed-meshheading:21342027-Histamine Release,
pubmed-meshheading:21342027-Intercellular Junctions,
pubmed-meshheading:21342027-Parietal Cells, Gastric,
pubmed-meshheading:21342027-Rats,
pubmed-meshheading:21342027-Rats, Sprague-Dawley,
pubmed-meshheading:21342027-Sigmodontinae
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pubmed:year |
2011
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pubmed:articleTitle |
Parietal cell activation by arborization of ECL cell cytoplasmic projections is likely the mechanism for histamine induced secretion of hydrochloric acid.
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pubmed:affiliation |
Department of Gastroenterology, St Olavs Hospital HF, Trondheim University Hospital, Trondheim, Norway. bjorn.gustafsson@ntnu.no
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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