Linked Life Data

21337756

Source:http://linkedlifedata.com/resource/pubmed/id/21337756

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
2011-2-18
pubmed:abstractText
The incidence of secondary malignancies (SM) was studied in a population of 219 patients in late periods (3-29 years) after childhood and adolescence chemoradiotherapy for Hodgkin's lymphoma (HL). SMs were found in 15 (6.8%) patients. These were solid neoplasms located in the irradiated areas in 12 of them, including 4 patients with thyroid cancer and 2 with gastric cancer. All 3 cases of acute leukemia had occurred after chemoradiotherapy performed by extended programs that consisted of a large number of chemotherapy cycles. The detection rate of SM did not significantly depend on the dose of radiation, age at start of treatment, and a child's gender. The findings suggest that there is a need for the maximum concentration of an irradiation beam in the area of thyroid lesion and exposure, for limited cytotoxic therapy programs, and lifetime medical observation of the patients treated for HL in childhood.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0042-4676
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7-9
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
[Secondary malignancies in late periods after chemoradiotherapy for lymphogranulomatosis in children].
pubmed:publicationType
Journal Article, English Abstract