Source:http://linkedlifedata.com/resource/pubmed/id/21334676
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2011-3-22
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pubmed:abstractText |
Prostate cancer cell proliferation is inhibited by 1a,25-dihydroxyvitamin D(3). Survivin is a member of the inhibitors of apoptosis protein family. Several studies indicate that survivin down-regulation sensitizes human tumor cells of different histological origins to conventional chemotherapeutic drugs. We assessed the effect of survivin gene expression on the proliferation of prostate cancer cells in vitro and in vivo. We also examined the antitumor sensitization effect of survivin inhibition in 1a,25-dihydroxyvitamin D(3) treatment for prostate cancer cells.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1527-3792
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
185
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1497-503
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pubmed:meshHeading |
pubmed-meshheading:21334676-Calcitriol,
pubmed-meshheading:21334676-Cell Proliferation,
pubmed-meshheading:21334676-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21334676-Humans,
pubmed-meshheading:21334676-Inhibitor of Apoptosis Proteins,
pubmed-meshheading:21334676-Male,
pubmed-meshheading:21334676-Prostatic Neoplasms,
pubmed-meshheading:21334676-Tumor Cells, Cultured
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pubmed:year |
2011
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pubmed:articleTitle |
Survivin is associated with cell proliferation and has a role in 1a,25-dihydroxyvitamin D3 induced cell growth inhibition in prostate cancer.
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pubmed:affiliation |
Department of Urology, Gunma University Graduate School of Medicine, Gunma, Japan. hkoike@med.gunma-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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