Linked Life Data

21330180

Source:http://linkedlifedata.com/resource/pubmed/id/21330180

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-2-28
pubmed:abstractText
Although spontaneous regression of cervical intraepithelial neoplasia type 2 (CIN 2) occurs in 40% of cases over a 2 years period, such diagnosis commonly requires the use of excisional techniques exposing to genuine obstetrical and neonatal morbidity as well as the risk of unsatisfactory post-treatment colposcopy. Recent advances in knowledge about CIN 2 natural history and morbidity of conservative therapies brings out the need to optimize therapeutics indications and to reconsider the use of ablative techniques. In order to allow for the lack of histological analysis and final diagnosis, it is therefore crucial not to misdiagnose microinvasive cervical disease. The use of factors significantly related to the risk of microinvasion misdiagnosis allows for a simple and reliable risk assessment in decision-making regarding CIN 2 management. Thus, CIN 2 therapeutic abstention with simple follow up as well as ablative technique might be safely considered in women under 30 whose lesion involves only one cervical quadrant, with type one transformation zone, without any colposcopic sign of severity and whose cervical smear and biopsy results are concordant. Use of ablative techniques will be recommended in all other cases. If necessary, practice of large loop excision of the transformation performed under colposcopic vision by experienced practitioner should be preferred to all other excisional techniques.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1769-6682
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Elsevier Masson SAS. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
94-9
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
[Should CIN 2 and 3 be treated the same way?].
pubmed:affiliation
Service de gynécologie-obstétrique, hôpital Nord, chemin des Bourrelly, 13015 Marseille, France. xcarco@free.fr
pubmed:publicationType
Journal Article, English Abstract, Review