Linked Life Data

21328141

Source:http://linkedlifedata.com/resource/pubmed/id/21328141

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2011-2-17
pubmed:abstractText
This study aims to explore and evaluate the effects of Semen Ziziphi Spinosae extracts on the serum levels of interleukin (IL)-6, IFN-?, IL-1?, TNF-?, IL-10 and IL-4 in mice, and the regulative effect of Semen Ziziphi Spinosae on the cytokine system. Using an ELISA assay, the serum levels of IL-6, IFN-?, IL-1?, TNF-?, IL-10 and IL-4 were examined in mice after intraperitoneal injection (i.p.) with Semen Ziziphi Spinosae extracts. The results showed that the levels of IL-6 and IL-1? were significantly increased compared with the control groups (p<0.01), while the level of tumour necrosis factor-? (TNF-?) was significantly decreased (p<0.01). Semen Ziziphi Spinosae possesses certain modulation effects on cytokines, and the immuno-regulating function and hypnosis effects of Semen Ziziphi Spinosae may be relevant to these modulation effects on cytokines.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1478-6427
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
464-7
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Modulation effect of Semen Ziziphi Spinosae extracts on IL-1?, IL-4, IL-6, IL-10, TNF-? and IFN-? in mouse serum.
pubmed:affiliation
Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin 300134, China. xjbo@tjcu.edu.cn
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't