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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-6-3
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pubmed:abstractText |
Colorectal cancer is the third most common cancer and a major cause of cancer-related deaths. Early detection of colonic lesions can reduce the incidence and mortality of colorectal cancer. Colonoscopy is the screening test for colorectal cancer with the highest efficacy, but its acceptance in the general public is rather low. To identify suitable tumor-derived markers that could detect colorectal cancer in blood samples, we analyzed the methylation status of a panel of genes in sera of affected patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1572-0241
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1110-8
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pubmed:meshHeading |
pubmed-meshheading:21326223-Adult,
pubmed-meshheading:21326223-Aged,
pubmed-meshheading:21326223-Aged, 80 and over,
pubmed-meshheading:21326223-Basic Helix-Loop-Helix Transcription Factors,
pubmed-meshheading:21326223-Case-Control Studies,
pubmed-meshheading:21326223-Colorectal Neoplasms,
pubmed-meshheading:21326223-DNA, Neoplasm,
pubmed-meshheading:21326223-DNA Methylation,
pubmed-meshheading:21326223-Early Detection of Cancer,
pubmed-meshheading:21326223-Female,
pubmed-meshheading:21326223-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21326223-Humans,
pubmed-meshheading:21326223-Male,
pubmed-meshheading:21326223-Middle Aged,
pubmed-meshheading:21326223-Nerve Tissue Proteins,
pubmed-meshheading:21326223-Pilot Projects,
pubmed-meshheading:21326223-ROC Curve,
pubmed-meshheading:21326223-Reference Values,
pubmed-meshheading:21326223-Statistics, Nonparametric,
pubmed-meshheading:21326223-Tumor Markers, Biological,
pubmed-meshheading:21326223-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Methylation of NEUROG1 in serum is a sensitive marker for the detection of early colorectal cancer.
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pubmed:affiliation |
Department of Medicine II, University of Munich, Munich, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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