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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1991-5-8
|
pubmed:abstractText |
4,4-Bis(4-fluorophenyl) butanoic acid is an important pharmaceutical intermediate. It is usually prepared by Friedel-Crafts reaction of 4-(4-fluorophenyl) butyrolactone with fluorobenzene. But the ratio of products is often affected by reaction conditions. By applying sulfonation, the undesired isomer can be successfully removed.
|
pubmed:language |
chi
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0513-4870
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
25
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
590-2
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading | |
pubmed:year |
1990
|
pubmed:articleTitle |
[Removal of the ortho isomer of 4,4-bis(4-fluoro phenyl) butanoic acid by sulfonation].
|
pubmed:affiliation |
Middle South Pharmaceutical Factory, Shaoyang.
|
pubmed:publicationType |
Journal Article,
English Abstract
|