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rdf:type |
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lifeskim:mentions |
umls-concept:C0020944,
umls-concept:C0026336,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0043240,
umls-concept:C0439596,
umls-concept:C0524865,
umls-concept:C1280500,
umls-concept:C1412125,
umls-concept:C1708715,
umls-concept:C2346689
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pubmed:issue |
4
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pubmed:dateCreated |
2011-2-17
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pubmed:abstractText |
Successful anterior cruciate ligament reconstruction with use of soft-tissue grafts requires healing between tendon and bone. Little is known about the effect of mechanical load on the cellular and molecular cascade of tendon-to-bone healing. Understanding these mechanical influences has critical implications for postoperative rehabilitation following anterior cruciate ligament reconstruction. The purpose of this study was to test the hypothesis that, compared with perioperative immobilization, short-duration low-magnitude cyclic axial loading would result in impaired tendon-to-bone healing after anterior cruciate ligament reconstruction in a rat model.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1535-1386
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
16
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
381-93
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pubmed:dateRevised |
2011-6-8
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pubmed:meshHeading |
pubmed-meshheading:21325590-Animals,
pubmed-meshheading:21325590-Anterior Cruciate Ligament,
pubmed-meshheading:21325590-Biomechanics,
pubmed-meshheading:21325590-Endothelium, Vascular,
pubmed-meshheading:21325590-External Fixators,
pubmed-meshheading:21325590-Femur,
pubmed-meshheading:21325590-Immobilization,
pubmed-meshheading:21325590-Macrophages,
pubmed-meshheading:21325590-Male,
pubmed-meshheading:21325590-Osteoblasts,
pubmed-meshheading:21325590-Osteoclasts,
pubmed-meshheading:21325590-Prosthesis Failure,
pubmed-meshheading:21325590-Rats,
pubmed-meshheading:21325590-Rats, Sprague-Dawley,
pubmed-meshheading:21325590-Tendons,
pubmed-meshheading:21325590-Tensile Strength,
pubmed-meshheading:21325590-Tibia,
pubmed-meshheading:21325590-Weight-Bearing,
pubmed-meshheading:21325590-Wound Healing,
pubmed-meshheading:21325590-X-Ray Microtomography
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pubmed:year |
2011
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pubmed:articleTitle |
Effect of short-duration low-magnitude cyclic loading versus immobilization on tendon-bone healing after ACL reconstruction in a rat model.
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pubmed:affiliation |
Laboratory for Soft Tissue Research, Hospital for Special Surgery, New York, NY, USA. brophyr@wudosis.wustl.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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