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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-4-25
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pubmed:abstractText |
Hepatocellular carcinoma (HCC) is a heterogeneous tumor that develops via activation of multiple pathways and molecular alterations. It has been a challenge to identify molecular classes of HCC and design treatment strategies for each specific subtype. MicroRNAs (miRNAs) are involved in HCC pathogenesis, and their expression profiles have been used to classify cancers. We analyzed miRNA expression in human HCC samples to identify molecular subclasses and oncogenic miRNAs.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1528-0012
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pubmed:author |
pubmed-author:AlsinetClaraC,
pubmed-author:BruixJordiJ,
pubmed-author:CabellosLaiaL,
pubmed-author:ChiangDerek YDY,
pubmed-author:FriedmanScott LSL,
pubmed-author:GolubToddT,
pubmed-author:HoshidaYujinY,
pubmed-author:LachenmayerAnjaA,
pubmed-author:LlovetJosep MJM,
pubmed-author:MazzaferroVincenzoV,
pubmed-author:MinguezBeatrizB,
pubmed-author:RoayaieSasanS,
pubmed-author:SavicRadoslavR,
pubmed-author:SchwartzMyronM,
pubmed-author:ThungSwanS,
pubmed-author:ToffaninSaraS,
pubmed-author:TovarVictoriaV,
pubmed-author:VillanuevaAugustoA,
pubmed-author:WardStephen CSC,
pubmed-author:WaxmanSamuelS
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pubmed:copyrightInfo |
Copyright © 2011 AGA Institute. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1618-28.e16
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pubmed:meshHeading |
pubmed-meshheading:21324318-Carcinoma, Hepatocellular,
pubmed-meshheading:21324318-Cell Line, Tumor,
pubmed-meshheading:21324318-Cell Proliferation,
pubmed-meshheading:21324318-Disease Progression,
pubmed-meshheading:21324318-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21324318-Humans,
pubmed-meshheading:21324318-Liver Neoplasms,
pubmed-meshheading:21324318-MicroRNAs,
pubmed-meshheading:21324318-Polymerase Chain Reaction,
pubmed-meshheading:21324318-RNA, Neoplasm,
pubmed-meshheading:21324318-Tumor Cells, Cultured
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pubmed:year |
2011
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pubmed:articleTitle |
MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a.
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pubmed:affiliation |
Mount Sinai Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, New York, New York, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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