Source:http://linkedlifedata.com/resource/pubmed/id/21321449
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2011-2-15
|
pubmed:abstractText |
We have developed a simple method to significantly improve the sensitivity in the LC/MS analysis of DNA adducts. A preconcentration tip for the selective recovery of DNA adducts was prepared. Using this tip, the total amount of DNA adducts in a treated DNA sample was injected in a one-shot manner into an LC/MS system. We were able to improve the sensitivity by more than one order of magnitude in concentration. This method will be a useful tool for the quantitative determination of trace DNA adducts.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1348-2246
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
27
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
217-20
|
pubmed:meshHeading | |
pubmed:year |
2011
|
pubmed:articleTitle |
Functional preconcentration tip of total volume injection for ESI/MS analysis of DNA adducts.
|
pubmed:affiliation |
Gifu Pharmaceutical University, Daigaku-nishi, Gifu 501-1196, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|