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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-4-25
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pubmed:abstractText |
Patients with irritable bowel syndrome with diarrhea (IBS-D) have increased mucosal serotonin (5-hydroxytryptamine [5-HT]) availability, possibly because immune activation reduces activity of the 5-HT transporter (SERT). We investigated the relationship between mucosal and platelet SERT and immune activation of the duodenal mucosa in patients with IBS-D.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1528-0012
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pubmed:author |
pubmed-author:BennettAndrewA,
pubmed-author:DuroudierNathalie PNP,
pubmed-author:FoleyStephenS,
pubmed-author:GarsedKlaraK,
pubmed-author:HallIan PIP,
pubmed-author:HolmesGeoffreyG,
pubmed-author:MarsdenCharlesC,
pubmed-author:SinghGulzarG,
pubmed-author:SpillerRobin CRC,
pubmed-author:SwanCarolineC,
pubmed-author:WallsAndrewA,
pubmed-author:ZaitounAbedA
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pubmed:copyrightInfo |
Copyright © 2011 AGA Institute. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1434-43.e1
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pubmed:meshHeading |
pubmed-meshheading:21315720-Adult,
pubmed-meshheading:21315720-Biological Transport,
pubmed-meshheading:21315720-Biopsy,
pubmed-meshheading:21315720-Blood Platelets,
pubmed-meshheading:21315720-Duodenum,
pubmed-meshheading:21315720-Female,
pubmed-meshheading:21315720-Gene Expression Regulation,
pubmed-meshheading:21315720-Humans,
pubmed-meshheading:21315720-Immunity, Cellular,
pubmed-meshheading:21315720-Intestinal Mucosa,
pubmed-meshheading:21315720-Irritable Bowel Syndrome,
pubmed-meshheading:21315720-Male,
pubmed-meshheading:21315720-Polymerase Chain Reaction,
pubmed-meshheading:21315720-RNA, Messenger,
pubmed-meshheading:21315720-Serotonin,
pubmed-meshheading:21315720-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:21315720-Signal Transduction
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pubmed:year |
2011
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pubmed:articleTitle |
Impaired uptake of serotonin by platelets from patients with irritable bowel syndrome correlates with duodenal immune activation.
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pubmed:affiliation |
National Institute for Health Research Biomedical Research Unit, Nottingham Digestive Diseases Centre, School of Clinical Sciences, Nottingham, England.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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