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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0015295,
umls-concept:C0030705,
umls-concept:C0032659,
umls-concept:C0238462,
umls-concept:C0694890,
umls-concept:C1513380,
umls-concept:C1553355,
umls-concept:C1554080,
umls-concept:C1706198,
umls-concept:C1880156,
umls-concept:C2603343
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|
pubmed:issue |
4
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|
pubmed:dateCreated |
2011-5-20
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|
pubmed:abstractText |
Germ-line mutations of RET proto-oncogene are the known cause of hereditary medullary thyroid carcinoma (MTC), which account for approximately 25% of all MTC cases and occur as multiple endocrine neoplasia type 2 syndromes. Here, we present the first comprehensive genetic screening and analysis of MTC among Iranian families.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
|
pubmed:issn |
1557-9077
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pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
21
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
373-82
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pubmed:dateRevised |
2011-10-2
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pubmed:meshHeading |
pubmed-meshheading:21309721-Adolescent,
pubmed-meshheading:21309721-Adult,
pubmed-meshheading:21309721-Aged,
pubmed-meshheading:21309721-Carcinoma, Medullary,
pubmed-meshheading:21309721-Child,
pubmed-meshheading:21309721-Exons,
pubmed-meshheading:21309721-Female,
pubmed-meshheading:21309721-Genetic Counseling,
pubmed-meshheading:21309721-Germ-Line Mutation,
pubmed-meshheading:21309721-Humans,
pubmed-meshheading:21309721-Iran,
pubmed-meshheading:21309721-Male,
pubmed-meshheading:21309721-Middle Aged,
pubmed-meshheading:21309721-Multiple Endocrine Neoplasia Type 2a,
pubmed-meshheading:21309721-Polymerase Chain Reaction,
pubmed-meshheading:21309721-Proto-Oncogene Proteins c-ret,
pubmed-meshheading:21309721-Thyroid Neoplasms
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|
pubmed:year |
2011
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|
pubmed:articleTitle |
Molecular analysis of the RET proto-oncogene key exons in patients with medullary thyroid carcinoma: a comprehensive study of the Iranian population.
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pubmed:affiliation |
Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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