Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1979-1-24
pubmed:abstractText
The distribution of two cell membrane enzymes, alkaline phosphatase and alkaline phosphodiesterase I has been studied in normal and leukaemic lymphocytes. No reduction in the level of activity of either enzyme was found in the chronic or acute B- and T-cell leukaemias. Alkaline phosphatase activity was elevated in the lymphocytes from T-CLL, cord blood and tonsils and the blast cells from Null-ALL. Alkaline phosphodiesterase was elevated in lymphocytes from cord blood and tonsils and the blast cells from Null-ALL. As findings in Null-ALL were based on only two cases, they need confirmation in a larger series. The significance of these results is discussed in relation to current theories of maturation and differentiation in the lymphoproliferative disorders.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0007-1048
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
111-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Cell membrane enzymes. II. Alkaline phosphatase and alkaline phosphodiesterase I in normal and leukaemic lymphocytes.
pubmed:publicationType
Journal Article