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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1991-11-7
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pubmed:abstractText |
The effects of an pretreatment course (2 x 5 days) combining vitamin E 20 mg/kg, anthocyans 50 mg/kg, and pyracetam 200 mg/kg on animal survival after lethal irradiation (8 Gy) and blood formation after sublethal irradiation (6 Gy) were studied in mice. Assessments were based on records of an integral criterion, 30-day survival, of spleen weight and cellularity, and of bone-marrow cellularity. Pretreatment with the mixture distinctly raised survival rate (50%) in the protected population. The effect observed was shown to result from potentiating interactions between mixture components. Blood-forming organs experienced less radiation damage, and recovery processes in them were stimulated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0323-9950
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
31-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2130627-Animals,
pubmed-meshheading:2130627-Anthocyanins,
pubmed-meshheading:2130627-Bone Marrow,
pubmed-meshheading:2130627-Bone Marrow Cells,
pubmed-meshheading:2130627-Bone Marrow Transplantation,
pubmed-meshheading:2130627-Drug Therapy, Combination,
pubmed-meshheading:2130627-Hematopoiesis,
pubmed-meshheading:2130627-Male,
pubmed-meshheading:2130627-Mice,
pubmed-meshheading:2130627-Mice, Inbred ICR,
pubmed-meshheading:2130627-Organ Size,
pubmed-meshheading:2130627-Piracetam,
pubmed-meshheading:2130627-Radiation-Protective Agents,
pubmed-meshheading:2130627-Spleen,
pubmed-meshheading:2130627-Vitamin E
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pubmed:year |
1990
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pubmed:articleTitle |
Antiradiation properties of alpha tocopherol, anthocyans, and pyracetam administered combined as a pretreatment course.
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pubmed:affiliation |
Research Institute of Nuclear Medicine, Radiobiology and Radiation Hygiene, Medical Academy, Sofia, Bulgaria.
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pubmed:publicationType |
Journal Article
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