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rdf:type |
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lifeskim:mentions |
umls-concept:C0003864,
umls-concept:C0015127,
umls-concept:C0021364,
umls-concept:C0026336,
umls-concept:C0026882,
umls-concept:C0031669,
umls-concept:C0205314,
umls-concept:C0243067,
umls-concept:C0311400,
umls-concept:C0591833,
umls-concept:C0679622,
umls-concept:C1314792,
umls-concept:C1533691
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pubmed:issue |
5
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pubmed:dateCreated |
2011-5-3
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pubmed:abstractText |
It is difficult to identify a single causative factor for inflammatory arthritis because of the multifactorial nature of the disease. This study was undertaken to dissect the molecular complexity of systemic inflammatory disease, utilizing a combined approach of mutagenesis and systematic phenotype screening in a murine model.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1529-0131
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pubmed:author |
pubmed-author:AbeKoichiroK,
pubmed-author:AdamskiJerzyJ,
pubmed-author:AdlerThureT,
pubmed-author:BoersmaAukeA,
pubmed-author:BuschDirk HDH,
pubmed-author:Calzada-WackJuliaJ,
pubmed-author:EspositoIreneI,
pubmed-author:FuchsHelmutH,
pubmed-author:Gailus-DurnerValerieV,
pubmed-author:HansWolfgangW,
pubmed-author:KalaydjievSvetoslavS,
pubmed-author:KametaniYoshieY,
pubmed-author:KatanMatildaM,
pubmed-author:KlaftenMatthiasM,
pubmed-author:KlingensporMartinM,
pubmed-author:MarasliogluMiriamM,
pubmed-author:MarschallSusanS,
pubmed-author:MossbruggerIlonaI,
pubmed-author:PrehnCorneliaC,
pubmed-author:RathkolbBirgitB,
pubmed-author:RozmanJanJ,
pubmed-author:ShimadaShinS,
pubmed-author:SoewartoDianD,
pubmed-author:WagnerSibylleS,
pubmed-author:WolfEckhardE,
pubmed-author:WurstWolfgangW,
pubmed-author:YuPhilippP,
pubmed-author:de AngelisMartin Hrab?MH
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pubmed:copyrightInfo |
Copyright © 2011 by the American College of Rheumatology.
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pubmed:issnType |
Electronic
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pubmed:volume |
63
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1301-11
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pubmed:meshHeading |
pubmed-meshheading:21305534-Animals,
pubmed-meshheading:21305534-Arthritis, Experimental,
pubmed-meshheading:21305534-Body Composition,
pubmed-meshheading:21305534-Ethylnitrosourea,
pubmed-meshheading:21305534-Flow Cytometry,
pubmed-meshheading:21305534-Infertility, Male,
pubmed-meshheading:21305534-Male,
pubmed-meshheading:21305534-Mice,
pubmed-meshheading:21305534-Mice, Mutant Strains,
pubmed-meshheading:21305534-Mutagenesis,
pubmed-meshheading:21305534-Mutation,
pubmed-meshheading:21305534-Phospholipase C gamma,
pubmed-meshheading:21305534-Polymorphism, Single Nucleotide,
pubmed-meshheading:21305534-Sperm Motility
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pubmed:year |
2011
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pubmed:articleTitle |
A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase C?2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model.
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pubmed:affiliation |
Tokai University School of Medicine, Kanagawa, Japan. abeko@is.icc.u-tokai.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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