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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1991-11-14
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pubmed:abstractText |
A comparative study of renin immunoreactivity in the juxtaglomerular apparatus of the human kidney was performed using the indirect immunoperoxidase method on a random microscopic sections. In renal biopsies taken from a case of Bartter's syndrome and a case of pseudo-Bartter's syndrome, the number of renin-positive juxtaglomerular apparatus (JGA) and the number of renin-positive cells in each JGA were significantly greater than in five renal specimens from control autopsy cases. In Conn's syndrome, none of the glomeruli contained renin-immunoreactive JGA. The number of renin-positive cells/mm2 in the renal cortex in cases of Bartter's and pseudo-Bartter's syndromes were 17.5 and 20.3, respectively, while in the control group, the range was 0.78-1.77 (mean 1.08). Together with other histochemical findings routinely examined in renal specimens, renin immunohistochemistry on random sections may be helpful in diagnostic renal pathology.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0385-0005
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
317-26
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2130539-Adult,
pubmed-meshheading:2130539-Bartter Syndrome,
pubmed-meshheading:2130539-Female,
pubmed-meshheading:2130539-Humans,
pubmed-meshheading:2130539-Hyperaldosteronism,
pubmed-meshheading:2130539-Immunohistochemistry,
pubmed-meshheading:2130539-Juxtaglomerular Apparatus,
pubmed-meshheading:2130539-Microscopy, Electron,
pubmed-meshheading:2130539-Microscopy, Immunoelectron,
pubmed-meshheading:2130539-Middle Aged,
pubmed-meshheading:2130539-Renin
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pubmed:year |
1990
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pubmed:articleTitle |
Functional interpretation of the kidney juxtaglomerular apparatus using renin immunohistochemistry in Bartter's, pseudo-Bartter's and Conn's syndromes.
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pubmed:affiliation |
Department of Pathology, School of Medicine, Tokai University, Kanagawa, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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