Linked Life Data

2130526

Source:http://linkedlifedata.com/resource/pubmed/id/2130526

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1991-11-13
pubmed:abstractText
Substantial evidence has been accumulated to support the gonadal regulation of immune functions. They are mainly based on the following observations: i) the existence of sexual dimorphism in immune response, ii) alteration of immune response by gonadectomy or sex steroid replacement, iii) alteration of immune response during pregnancy, and iv) existence of sex steroid receptors in the thymus tissue which affect T cell function through thymic hormones produced in the gland. In the present study, we have tried to review some of this evidence by adding our own findings. We also referred to the experimental findings which show that the thymus, brain and gonads are close-related functionally, and form a functional axis, the so-called "hypothalamic-pituitary-gonadal-thymic" axis which is of great importance not only because it regulates immune response, but because its influence may extend to other organ system within the living body.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0385-0005
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-9
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Hormone and immune response, with special reference to steroid hormone 1. A short review.
pubmed:affiliation
Department of Anatomy, School of Medicine, Tokai University, Kanagawa, Japan.
pubmed:publicationType
Journal Article, Review