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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-5-31
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pubmed:abstractText |
Acute administration of the antitumoral drug cisplatin can induce nausea/emesis and diarrhea. The long-term effects of cisplatin on gastrointestinal motility, particularly after repeated administration, are not well known. Because cisplatin is highly neurotoxic, myenteric neurons can be affected. Our aim was to study the prolonged effects of repeated cisplatin administration in a rat model, focusing on gastrointestinal motor function and myenteric neurons.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1365-2982
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pubmed:author |
pubmed-author:AbaloRR,
pubmed-author:BarbaraGG,
pubmed-author:CabezosP APA,
pubmed-author:CastilloMM,
pubmed-author:ChiarloneAA,
pubmed-author:CorinaldesiRR,
pubmed-author:De GiorgioRR,
pubmed-author:GoriAA,
pubmed-author:MartínM IMI,
pubmed-author:PasquinelliGG,
pubmed-author:StanghelliniVV,
pubmed-author:VeraGG
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pubmed:copyrightInfo |
© 2011 Blackwell Publishing Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
370-8, e162-3
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pubmed:meshHeading |
pubmed-meshheading:21299719-Animals,
pubmed-meshheading:21299719-Antineoplastic Agents,
pubmed-meshheading:21299719-Calcitonin Gene-Related Peptide,
pubmed-meshheading:21299719-Cisplatin,
pubmed-meshheading:21299719-Disease Models, Animal,
pubmed-meshheading:21299719-Dose-Response Relationship, Drug,
pubmed-meshheading:21299719-Enteric Nervous System,
pubmed-meshheading:21299719-Gastrointestinal Diseases,
pubmed-meshheading:21299719-Gastrointestinal Motility,
pubmed-meshheading:21299719-Male,
pubmed-meshheading:21299719-Myenteric Plexus,
pubmed-meshheading:21299719-Nervous System Diseases,
pubmed-meshheading:21299719-Neurons,
pubmed-meshheading:21299719-Nitric Oxide Synthase,
pubmed-meshheading:21299719-Rats,
pubmed-meshheading:21299719-Rats, Wistar
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pubmed:year |
2011
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pubmed:articleTitle |
Enteric neuropathy evoked by repeated cisplatin in the rat.
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pubmed:affiliation |
Department of Pharmacology and Nutrition, Rey Juan Carlos University, Alcorcón, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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