Linked Life Data

21298667

Source:http://linkedlifedata.com/resource/pubmed/id/21298667

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2011-2-7
pubmed:abstractText
Nanoparticles exhibiting favorable surface-to-volume ratios create efficient stationary phases for electrochromatography. New nanomaterials derived from chitosan (CS) were immobilized onto modified capillaries for use as the chiral stationary phase (CSP) in open-tubular electrochromatography. This immobilization was achieved through the copolymerization of glycidyl methacrylate-modified nano-CS with methacrylamide (MAA) and bis-acrylamide crosslinkers (forming the MAA-CS capillary) rather than the attachment of nano-CS to the copolymer of glycidyl methacrylate, MAA, and bis-acrylamide (forming the MAA+CS capillary). The completed MAA-CS capillary and its precursors were examined by SEM and ATR-IR measurements. Before separating chiral samples, the MAA-CS capillary was characterized by electroosmotic flow measurements at varying pH values, concentrations, and volume percentages of organic modifiers in the running buffers. Tryptophan enantiomers were well separated by the MAA-CS capillary, whereas no enantioselectivity was observed in the MAA+CS capillary. With the addition of 80% MeOH into the phosphate buffer, the chiral separation of (±)-catechin was accomplished in a normal-phase mode. However, the new CSP has its limitations, as only two groups of ?-tocopherol stereoisomers were separated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1522-2683
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
pubmed:issnType
Electronic
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
398-407
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Nanochitosan crosslinked with polyacrylamide as the chiral stationary phase for open-tubular capillary electrochromatography.
pubmed:affiliation
School of Pharmacy, China Medical University, Taichung, Taiwan. cjl@mail.cmu.edu.tw
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't