Linked Life Data

2129574

Source:http://linkedlifedata.com/resource/pubmed/id/2129574

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-11-8
pubmed:abstractText
The authors present the case of a 9-month-old child with clinical dilated cardiomyopathy that at necropsy showed myocardial cells with volumous, bizarre, and pleomorphic nuclei. These nuclear alterations were also found in other tissues. The myocardial ultrastructural studies revealed degenerative cytoplasmatic changes, nuclear membrane invaginations forming tubules, vesicles, and cytoplasmatic pseudoinclusions, and intranuclear vermicelar bodies, which all suggest virus-induced lesions. Although the ultrastructural studies and immunoperoxidase tests for virus identification were negative, the authors believe that a virus is most probably the agent of these alterations. This case seems to be the first reported on dilated cardiomyopathy with bizarre nuclear alterations in the myocardial fibers having strong evidence pointing to viral etiology.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0887-8005
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
321-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Bizarre nuclei of myocardial fibers in an infant with dilated cardiomyopathy. Light, electron-microscopic, and immunoperoxidase studies of a necropsy case.
pubmed:affiliation
Department of Pathology, Federal Fluminense University, Niterói, Rio de Janeiro, Brasil.
pubmed:publicationType
Journal Article, Case Reports