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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1991-10-7
|
| pubmed:abstractText |
Fractional shortening/end-systolic stress (FS/ESS) correlation by echocardiography is a reliable index of left ventricular function. Acetate infusion or preload reduction due to water compartment re-equilibrium may induce ventricular derangements during dialytic treatment. In 13 patients on lactate haemofiltration (LHF) (mean age 56.8 +/- 11.9 years on regular dialytic treatment (RDT) for 75.3 +/- 56.5 months) and in seven patients on acetate haemodialysis (AHD) (mean age 48 +/- 10.7 years; on RDT for 43.9 +/- 49.2 months) fractional shortening/end-systolic stress was evaluated before and after single dialytic session. The following biochemical parameters were also studied: haematocrit (Htc), plasmatic osmolarity, ionised Ca, Na, K, and blood gases. In both groups the mean fractional shortening/end-systolic stress correlation maintained the same correlation coefficient before and after treatment (r = -0.68, P less than 0.001). Lactate haemofiltration and acetate haemodialysis by reducing the volume expansion and preload (mean interdialytic body-weight increase 2.5 +/- 0.8 kg in our patients), may decrease left ventricular contractility (Starling's law). Furthermore, acetate was postulated as a myocardial depressant. Dialysis-induced myocardial contractility variations plotted against fractional shortening/end-systolic stress correlation allowed the division of our patients into four different groups: (1) patients with increased fractional shortening and reduced end-systolic stress; (2) patients with unchanged fractional shortening and reduced end-systolic stress; (3) patients with reduced fractional shortening and increased end-systolic stress; and (4) patients with reduced fractional shortening and unchanged or reduced end-systolic stress. These groups include patients treated with either lactate haemofiltration or acetate haemodialysis. Our data cannot confirm the postulated acetate myocardial depressant activity.(ABSTRACT TRUNCATED AT 250 WORDS)
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0931-0509
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
5 Suppl 1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
115-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2129439-Acetic Acid,
pubmed-meshheading:2129439-Acetic Acids,
pubmed-meshheading:2129439-Adult,
pubmed-meshheading:2129439-Aged,
pubmed-meshheading:2129439-Female,
pubmed-meshheading:2129439-Hemofiltration,
pubmed-meshheading:2129439-Humans,
pubmed-meshheading:2129439-Lactates,
pubmed-meshheading:2129439-Lactic Acid,
pubmed-meshheading:2129439-Male,
pubmed-meshheading:2129439-Middle Aged,
pubmed-meshheading:2129439-Myocardial Contraction,
pubmed-meshheading:2129439-Renal Dialysis,
pubmed-meshheading:2129439-Ventricular Function, Left
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Fractional shortening/end-systolic stress correlation in the evaluation of left ventricular contractility in patients treated by acetate dialysis and lactate haemofiltration.
|
| pubmed:affiliation |
Medical Clinic II Institute, University of Pisa, Italy.
|
| pubmed:publicationType |
Journal Article
|