Source:http://linkedlifedata.com/resource/pubmed/id/21291585
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2011-2-4
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pubmed:abstractText |
Information about the spectrum of disease caused by hepatitis E virus (HEV) genotype 3 is emerging. During 2004-2009, at 2 hospitals in the United Kingdom and France, among 126 patients with locally acquired acute and chronic HEV genotype 3 infection, neurologic complications developed in 7 (5.5%): inflammatory polyradiculopathy (n = 3), Guillain-Barre syndrome (n = 1), bilateral brachial neuritis (n = 1), encephalitis (n = 1), and ataxia/proximal myopathy (n = 1). Three cases occurred in nonimmunocompromised patients with acute HEV infection, and 4 were in immunocompromised patients with chronic HEV infection. HEV RNA was detected in cerebrospinal fluid of all 4 patients with chronic HEV infection but not in that of 2 patients with acute HEV infection. Neurologic outcomes were complete resolution (n = 3), improvement with residual neurologic deficit (n = 3), and no improvement (n = 1). Neurologic disorders are an emerging extrahepatic manifestation of HEV infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1080-6059
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pubmed:author |
pubmed-author:BendallRichard PRP,
pubmed-author:CintasPascalP,
pubmed-author:DaltonHarry RHR,
pubmed-author:IjazSamreenS,
pubmed-author:IzopetJacquesJ,
pubmed-author:KamarNassimN,
pubmed-author:KeaneFrancesF,
pubmed-author:MansuyJean MichelJM,
pubmed-author:PeronJean MarieJM,
pubmed-author:PrudhommeLaurentL,
pubmed-author:RostaingLionelL
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
173-9
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pubmed:dateRevised |
2011-11-3
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pubmed:meshHeading |
pubmed-meshheading:21291585-Acute Disease,
pubmed-meshheading:21291585-Adult,
pubmed-meshheading:21291585-Chronic Disease,
pubmed-meshheading:21291585-Female,
pubmed-meshheading:21291585-France,
pubmed-meshheading:21291585-Great Britain,
pubmed-meshheading:21291585-Guillain-Barre Syndrome,
pubmed-meshheading:21291585-Hepatitis E,
pubmed-meshheading:21291585-Hepatitis E virus,
pubmed-meshheading:21291585-Humans,
pubmed-meshheading:21291585-Male,
pubmed-meshheading:21291585-Middle Aged,
pubmed-meshheading:21291585-Nervous System Diseases
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pubmed:year |
2011
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pubmed:articleTitle |
Hepatitis E virus and neurologic disorders.
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pubmed:affiliation |
Department of Nephrology, Dialysis and Organ Transplantation, Centre Hospitalier Universitaire Rangueil, Toulouse, France. kamar.n@chu-toulouse.fr
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
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