|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2011-3-11
|
|
pubmed:abstractText |
It has recently been suggested that long-term continuous treatment with bisphosphonates can eventually result in skeletal harm. We reported that the level of urinary cross-linked N-telopeptide of type I collagen (NTX) was over-reduced in 11 of 87 (12.7%) patients receiving long-term therapy with bisphosphonates. In this case, it is inconclusive whether treatment with bisphosphonates should be continued or not after over-reduction of bone resorption markers. In this study, we demonstrated changes in NTX levels in 13 patients who consented to continue treatment with bisphosphonates even after the over-reduction of NTX levels.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
1436-2023
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
16
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
71-6
|
|
pubmed:meshHeading |
pubmed-meshheading:21290152-Absorptiometry, Photon,
pubmed-meshheading:21290152-Aged,
pubmed-meshheading:21290152-Aged, 80 and over,
pubmed-meshheading:21290152-Biological Markers,
pubmed-meshheading:21290152-Bone Density,
pubmed-meshheading:21290152-Collagen Type I,
pubmed-meshheading:21290152-Diphosphonates,
pubmed-meshheading:21290152-Dose-Response Relationship, Drug,
pubmed-meshheading:21290152-Female,
pubmed-meshheading:21290152-Follow-Up Studies,
pubmed-meshheading:21290152-Humans,
pubmed-meshheading:21290152-Male,
pubmed-meshheading:21290152-Middle Aged,
pubmed-meshheading:21290152-Osteoporosis,
pubmed-meshheading:21290152-Peptides,
pubmed-meshheading:21290152-Retrospective Studies,
pubmed-meshheading:21290152-Risk Factors,
pubmed-meshheading:21290152-Time Factors,
pubmed-meshheading:21290152-Treatment Outcome
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Course of NTX changes under continuous bisphosphonate treatment in cases of NTX over-reduction due to long-term treatment with bisphosphonates.
|
|
pubmed:affiliation |
Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan. iba@sapmed.ac.jp
|
|
pubmed:publicationType |
Journal Article,
Comparative Study
|
