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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2011-3-1
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pubmed:abstractText |
Multiple sclerosis (MS) in the pediatric age group is being increasingly recognized. In adults, complex interactions between genetic and environmental factors contribute to risk and the major genetic component of MS susceptibility localizes to the major histocompatibility complex (human leukocyte antigen [HLA]). Whether HLA alleles predict MS in at-risk children presenting with acquired demyelinating syndromes (ADS) of the CNS is unknown.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-11865153,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-12940836,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-1357775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-14760270,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-15778816,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-16186814,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-16283615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-16717206,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-17438241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-17689148,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-17884679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-19153370,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-21288985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-8560455,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21288988-9706723
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
781-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21288988-Adolescent,
pubmed-meshheading:21288988-Age of Onset,
pubmed-meshheading:21288988-Alleles,
pubmed-meshheading:21288988-Child,
pubmed-meshheading:21288988-Child, Preschool,
pubmed-meshheading:21288988-Demyelinating Diseases,
pubmed-meshheading:21288988-Female,
pubmed-meshheading:21288988-Follow-Up Studies,
pubmed-meshheading:21288988-Genetic Predisposition to Disease,
pubmed-meshheading:21288988-HLA-DR Antigens,
pubmed-meshheading:21288988-HLA-DRB1 Chains,
pubmed-meshheading:21288988-Humans,
pubmed-meshheading:21288988-Infant,
pubmed-meshheading:21288988-Longitudinal Studies,
pubmed-meshheading:21288988-Male,
pubmed-meshheading:21288988-Multiple Sclerosis,
pubmed-meshheading:21288988-Mutation,
pubmed-meshheading:21288988-Prospective Studies,
pubmed-meshheading:21288988-Risk Factors
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pubmed:year |
2011
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pubmed:articleTitle |
HLA-DRB1 confers increased risk of pediatric-onset MS in children with acquired demyelination.
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pubmed:affiliation |
McGill University, Montreal Neurological Institute, Montreal, Quebec, H3A2B4, Canada.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
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