Linked Life Data

21287247

Source:http://linkedlifedata.com/resource/pubmed/id/21287247

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-4-11
pubmed:abstractText
In this study, the self-organized TiO(2) nanotubes grown by anodization of Ti-4Zr-22Nb-2Sn at different potentials, concentration of NH(4)F and anodization time was investigated. The morphology of nanotubes was observed by FE-SEM. The drug-loaded nanotubes were also fabricated in aqueous media containing minocycline hydrochloride. They were characterized by SEM, XPS and FT-IR. The results showed that the drug of minocycline hydrochloride (MH) was loaded in the nanotubes. The release effects were studied in phosphate buffer solution (PBS). The release rate of MH from TiO(2) nanotubes with shorter tube length in PBS was lower than the one of MH from longer nanotubes. The sustaining release time could last at least 150 h. Hence, it is a promising method to eliminate the harmful reactions by carrying drug in the tubes when the titanium alloys were used as biomedical implants.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1573-4838
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
461-7
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Characterization of self-organized TiO2 nanotubes on Ti-4Zr-22Nb-2Sn alloys and the application in drug delivery system.
pubmed:affiliation
School of Materials Science and Engineering, Tianjin University, Tianjin, 300072, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't