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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-4-6
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pubmed:databankReference |
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pubmed:abstractText |
Live-attenuated influenza vaccine (LAIV) protects against influenza by mucosal activation of the immune system. Studies in animals and adults have demonstrated that probiotics improve the immune response to mucosally delivered vaccines. We hypothesized that Lactobacillus GG (LGG) would function as an immune adjuvant to increase rates of seroconversion after LAIV administration.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1476-5640
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pubmed:author |
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pubmed:copyrightInfo |
© 2011 Macmillan Publishers Limited All rights reserved
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pubmed:issnType |
Electronic
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
501-7
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pubmed:dateRevised |
2011-10-3
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pubmed:meshHeading |
pubmed-meshheading:21285968-Adjuvants, Immunologic,
pubmed-meshheading:21285968-Adolescent,
pubmed-meshheading:21285968-Adult,
pubmed-meshheading:21285968-Antibodies, Viral,
pubmed-meshheading:21285968-Double-Blind Method,
pubmed-meshheading:21285968-Drug Toxicity,
pubmed-meshheading:21285968-Female,
pubmed-meshheading:21285968-Hemagglutination Inhibition Tests,
pubmed-meshheading:21285968-Humans,
pubmed-meshheading:21285968-Influenza, Human,
pubmed-meshheading:21285968-Influenza A Virus, H1N1 Subtype,
pubmed-meshheading:21285968-Influenza A Virus, H3N2 Subtype,
pubmed-meshheading:21285968-Influenza Vaccines,
pubmed-meshheading:21285968-Lactobacillus,
pubmed-meshheading:21285968-Male,
pubmed-meshheading:21285968-Pilot Projects,
pubmed-meshheading:21285968-Probiotics,
pubmed-meshheading:21285968-Vaccines, Attenuated,
pubmed-meshheading:21285968-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Lactobacillus GG as an immune adjuvant for live-attenuated influenza vaccine in healthy adults: a randomized double-blind placebo-controlled trial.
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pubmed:affiliation |
Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts Medical Center, Boston, MA 02111, USA. ldavidson1@tuftsmedicalcenter.org
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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