rdf:type |
|
lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0006674,
umls-concept:C0028912,
umls-concept:C0036043,
umls-concept:C0040808,
umls-concept:C0055895,
umls-concept:C0220825,
umls-concept:C0332283,
umls-concept:C0406317,
umls-concept:C1154182,
umls-concept:C1273870,
umls-concept:C1300563,
umls-concept:C1519252,
umls-concept:C1704413,
umls-concept:C2603343
|
pubmed:issue |
2
|
pubmed:dateCreated |
2011-2-1
|
pubmed:abstractText |
Psoriasis is a hyperproliferative and inflammatory skin disorder that affects roughly 2 percent of the worldwide population. Clobetasol propionate is the most common corticosteroid used to treat moderate-to-severe psoriasis but the potential for side effects limits its long-term use. Topical vitamin D, which is used to treat mild-to-moderate psoriasis, has been shown to be safe when used daily for up to 52 weeks. To date, very few studies exist evaluating the use of clobetasol propionate in a regimen with calcitriol to manage moderate-to-severe disease over time.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1545-9616
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
158-64
|
pubmed:meshHeading |
pubmed-meshheading:21283920-Administration, Cutaneous,
pubmed-meshheading:21283920-Anti-Inflammatory Agents,
pubmed-meshheading:21283920-Calcitriol,
pubmed-meshheading:21283920-Clobetasol,
pubmed-meshheading:21283920-Disease Progression,
pubmed-meshheading:21283920-Drug Administration Schedule,
pubmed-meshheading:21283920-Drug Therapy, Combination,
pubmed-meshheading:21283920-Female,
pubmed-meshheading:21283920-Humans,
pubmed-meshheading:21283920-Male,
pubmed-meshheading:21283920-Psoriasis,
pubmed-meshheading:21283920-Time Factors,
pubmed-meshheading:21283920-Treatment Outcome,
pubmed-meshheading:21283920-Vitamins
|
pubmed:year |
2011
|
pubmed:articleTitle |
A multi-center, open-label study to evaluate the safety and efficacy of a sequential treatment regimen of clobetasol propionate 0.05% spray followed by Calcitriol 3 mg/g ointment in the management of plaque psoriasis.
|
pubmed:affiliation |
Northeastern Ohio Universities, College of Medicine, Warren, OH, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|