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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-2-1
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pubmed:abstractText |
There is an unmet need to monitor human and natural environments for substances that are intentionally or unintentionally introduced. A long-sought goal is to adapt plants to sense and respond to specific substances for use as environmental monitors. Computationally re-designed periplasmic binding proteins (PBPs) provide a means to design highly sensitive and specific ligand sensing capabilities in receptors. Input from these proteins can be linked to gene expression through histidine kinase (HK) mediated signaling. Components of HK signaling systems are evolutionarily conserved between bacteria and plants. We previously reported that in response to cytokinin-mediated HK activation in plants, the bacterial response regulator PhoB translocates to the nucleus and activates transcription. Also, we previously described a plant visual response system, the de-greening circuit, a threshold sensitive reporter system that produces a visual response which is remotely detectable and quantifiable.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-10659857,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-10911994,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-10938857,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-10966457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-11110912,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-11973328,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-12451174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-12644681,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-12687005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-12736688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-14503005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-14581621,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-15148405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-15218149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-15313245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-15454422,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-15618507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-16823040,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-16901781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-16929106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-17309732,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-17379809,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-18182014,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-18248418,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-18970171,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-19371748,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-19455134,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-19720520,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-19833875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-19853288,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-8106326,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-8432742,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21283542-8809768
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:AlbrechtKirk DKD,
pubmed-author:AntunesMauricio SMS,
pubmed-author:BowenTessa ATA,
pubmed-author:CuneoMatthew JMJ,
pubmed-author:HellingaHomme WHW,
pubmed-author:MedfordJune IJI,
pubmed-author:MoreyKevin JKJ,
pubmed-author:SmithJ JeffJJ,
pubmed-author:TroupeJared FJF,
pubmed-author:WebbColleen TCT,
pubmed-author:ZdunekJeffrey KJK
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e16292
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pubmed:meshHeading |
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pubmed:year |
2011
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pubmed:articleTitle |
Programmable ligand detection system in plants through a synthetic signal transduction pathway.
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pubmed:affiliation |
Department of Biology, Colorado State University, Fort Collins, Colorado, United States of America.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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