Inflammatory bowel disease (IBD) of pediatric and adult onset differs in several aspects although little knowledge exists about pathogenic disparity. Regulatory T cells (Tregs) characterized as CD4+CD25+Foxp3+ are modulators of gut homeostasis, but their role in human IBD remains unclear.
Centre for Immune Regulation, Laboratory for Immunohistochemistry and Immunopathology, Department of Pathology, University of Oslo, Oslo, Norway. Dag.Henrik.Reikvam@rr-research.no