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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-1-31
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pubmed:abstractText |
Multiple sclerosis (MS) is a multifactorial neurologic disease characterized by modest but tractable heritability. Genome-wide association studies have identified and/or validated multiple polymorphisms in approximately 16 genes associated with susceptibility. We aimed at investigating the aggregation of genetic MS risk markers in individuals by comparing multiple- and single-case families.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1531-8249
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 American Neurological Association.
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pubmed:issnType |
Electronic
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
65-74
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21280076-Adult,
pubmed-meshheading:21280076-Alleles,
pubmed-meshheading:21280076-Case-Control Studies,
pubmed-meshheading:21280076-Chromosome Mapping,
pubmed-meshheading:21280076-Family,
pubmed-meshheading:21280076-Female,
pubmed-meshheading:21280076-Genetic Heterogeneity,
pubmed-meshheading:21280076-Genetic Predisposition to Disease,
pubmed-meshheading:21280076-Genetic Variation,
pubmed-meshheading:21280076-Genome-Wide Association Study,
pubmed-meshheading:21280076-Genotype,
pubmed-meshheading:21280076-HLA-DR Antigens,
pubmed-meshheading:21280076-HLA-DRB1 Chains,
pubmed-meshheading:21280076-Humans,
pubmed-meshheading:21280076-Male,
pubmed-meshheading:21280076-Multiple Sclerosis,
pubmed-meshheading:21280076-Pedigree,
pubmed-meshheading:21280076-Polymorphism, Genetic,
pubmed-meshheading:21280076-Polymorphism, Single Nucleotide,
pubmed-meshheading:21280076-Risk Factors
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pubmed:year |
2011
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pubmed:articleTitle |
Aggregation of multiple sclerosis genetic risk variants in multiple and single case families.
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pubmed:affiliation |
Department of Neurology, School of Medicine, University of California at San Francisco, San Francisco, CA, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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