21278242

Source:http://linkedlifedata.com/resource/pubmed/id/21278242

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0030705, umls-concept:C0205179, umls-concept:C0243044, umls-concept:C0280100, umls-concept:C0920321, umls-concept:C1442162, umls-concept:C1527262, umls-concept:C1550718, umls-concept:C1999216
pubmed:issue	6
pubmed:dateCreated	2011-3-17
pubmed:abstractText	A phase I study to define toxicity and recommend a phase II dose of the HSP90 inhibitor alvespimycin (17-DMAG; 17-dimethylaminoethylamino-17-demethoxygeldanamycin). Secondary endpoints included evaluation of pharmacokinetic profile, tumor response, and definition of a biologically effective dose (BED).
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/A5847, http://linkedlifedata.com/resource/pubmed/grant/C212/A11342, http://linkedlifedata.com/resource/pubmed/grant/C212/A5720, http://linkedlifedata.com/resource/pubmed/grant/C212/A7324, http://linkedlifedata.com/resource/pubmed/grant/C309/A8274, http://linkedlifedata.com/resource/pubmed/grant/CRUKD/06/052
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/17-(dimethylaminoethylamino)-17-deme..., http://linkedlifedata.com/resource/pubmed/chemical/Benzoquinones, http://linkedlifedata.com/resource/pubmed/chemical/HSP90 Heat-Shock Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Lactams, Macrocyclic
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	1078-0432
pubmed:author	pubmed-author:AherneWynneW, pubmed-author:ArkenauHendrik-TobiasHT, pubmed-author:BanerjiUdaiU, pubmed-author:EatockMartin MMM, pubmed-author:HardcastleAntheaA, pubmed-author:JudsonIanI, pubmed-author:Moreno-FarreJavierJ, pubmed-author:PaceySimonS, pubmed-author:PeacheyHeidiH, pubmed-author:RaynaudFlorenceF, pubmed-author:RoelsBelleB, pubmed-author:WaltonMikeM, pubmed-author:WilsonRichard HRH, pubmed-author:WorkmanPaulP, pubmed-author:ZetterlundAnnaA, pubmed-author:de BonoJohan SJS
pubmed:copyrightInfo	©2011 AACR.
pubmed:issnType	Print
pubmed:day	15
pubmed:volume	17
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1561-70
pubmed:dateRevised	2011-9-16
pubmed:meshHeading	pubmed-meshheading:21278242-Humans, pubmed-meshheading:21278242-Neoplasms, pubmed-meshheading:21278242-Biopsy, pubmed-meshheading:21278242-Aged

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