|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0033927,
umls-concept:C0036341,
umls-concept:C0205245,
umls-concept:C0314603,
umls-concept:C0392756,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0681850,
umls-concept:C1513371,
umls-concept:C1550501,
umls-concept:C1552599,
umls-concept:C1704243,
umls-concept:C1704787,
umls-concept:C1706203,
umls-concept:C1707489,
umls-concept:C1708715,
umls-concept:C1882071,
umls-concept:C2346689,
umls-concept:C2349001,
umls-concept:C2697811,
umls-concept:C2828024
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pubmed:issue |
1-3
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pubmed:dateCreated |
2011-3-8
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pubmed:abstractText |
Neuroimaging studies in subjects at genetic high risk (GHR) of schizophrenia can provide clues to the causes for the development of schizophrenia. Little is known about genetic influence on functional connectivity status, although studies on schizophrenia have reported an abnormal default mode network (DMN). We sought to identify putative genetic vulnerability markers by examining whether aberrant DMN connectivity was present in GHR subjects with high genetic loading.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1573-2509
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
58-65
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pubmed:meshHeading |
pubmed-meshheading:21277171-Adolescent,
pubmed-meshheading:21277171-Adult,
pubmed-meshheading:21277171-Brain Mapping,
pubmed-meshheading:21277171-Case-Control Studies,
pubmed-meshheading:21277171-Female,
pubmed-meshheading:21277171-Humans,
pubmed-meshheading:21277171-Magnetic Resonance Imaging,
pubmed-meshheading:21277171-Male,
pubmed-meshheading:21277171-Nerve Net,
pubmed-meshheading:21277171-Neural Pathways,
pubmed-meshheading:21277171-Neuropsychological Tests,
pubmed-meshheading:21277171-Prefrontal Cortex,
pubmed-meshheading:21277171-Psychiatric Status Rating Scales,
pubmed-meshheading:21277171-Psychotic Disorders,
pubmed-meshheading:21277171-Schizophrenia,
pubmed-meshheading:21277171-Statistics, Nonparametric,
pubmed-meshheading:21277171-Statistics as Topic,
pubmed-meshheading:21277171-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Reduced prefrontal functional connectivity in the default mode network is related to greater psychopathology in subjects with high genetic loading for schizophrenia.
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pubmed:affiliation |
Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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