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rdf:type |
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lifeskim:mentions |
umls-concept:C0008976,
umls-concept:C0011155,
umls-concept:C0012634,
umls-concept:C0025810,
umls-concept:C0034656,
umls-concept:C0040332,
umls-concept:C0162429,
umls-concept:C0337664,
umls-concept:C0424295,
umls-concept:C0473169,
umls-concept:C1522326
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pubmed:dateCreated |
2011-2-15
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pubmed:abstractText |
Methylphenidate blocks the re-uptake of dopamine by binding to the dopamine transporter in the presynaptic cell membrane and increases extracellular dopamine levels. Similarities in neuropsychologic effects between nicotine and methylphenidate make it an intriguing potential therapeutic option. Previous research of methylphenidate in smokers has suggested a possible beneficial effect for the relief of nicotine withdrawal symptoms, but showed no efficacy in helping smokers with attention deficit hyperactivity disorder (ADHD) to stop smoking.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-12745505,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-15983792,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-17447052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-18778120,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-19184649,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-1929025,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-1935872,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-20081039,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-20492837,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-20590478,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-7484329,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21276244-9766762
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1477-5751
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1
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pubmed:dateRevised |
2011-7-25
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pubmed:meshHeading |
pubmed-meshheading:21276244-Adult,
pubmed-meshheading:21276244-Aged,
pubmed-meshheading:21276244-Attention Deficit Disorder with Hyperactivity,
pubmed-meshheading:21276244-Female,
pubmed-meshheading:21276244-Humans,
pubmed-meshheading:21276244-Male,
pubmed-meshheading:21276244-Methylphenidate,
pubmed-meshheading:21276244-Middle Aged,
pubmed-meshheading:21276244-Nicotine,
pubmed-meshheading:21276244-Pilot Projects,
pubmed-meshheading:21276244-Placebos,
pubmed-meshheading:21276244-Smoking,
pubmed-meshheading:21276244-Substance Withdrawal Syndrome,
pubmed-meshheading:21276244-Tobacco Use Disorder,
pubmed-meshheading:21276244-Treatment Outcome,
pubmed-meshheading:21276244-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Methylphenidate for treating tobacco dependence in non-attention deficit hyperactivity disorder smokers: a pilot randomized placebo-controlled trial.
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pubmed:affiliation |
Nicotine Dependence Center, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA. rhurt@mayo.edu
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, N.I.H., Extramural
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