Linked Life Data

21276002

Source:http://linkedlifedata.com/resource/pubmed/id/21276002

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2011-1-31
pubmed:abstractText
Over the past two decades our view of adipose tissue has undergone a dramatic change from an inert energy storage tissue to an active endocrine organ. Adipose tissue communicates with other central and peripheral organs by synthesis and secretion of a host of molecules that we generally refer to as adipokines. The levels of some adipokines correlate with specific metabolic states and have the potential to impact directly upon the metabolic homeostasis of the system. A dysregulation of adipokines has been implicated in obesity, type 2 diabetes, hypertension, cardiovascular disease, and an ever-growing larger list of pathological changes in a number of organs. Here, we review the recent progress regarding the synthesis, secretion, and physiological function of adipokines with perspectives on future directions and potential therapeutic goals.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1749-6632
pubmed:author
pubmed:copyrightInfo
© 2010 New York Academy of Sciences.
pubmed:issnType
Electronic
pubmed:volume
1212
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
E1-E19
pubmed:dateRevised
2011-11-1
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Adipokines as novel biomarkers and regulators of the metabolic syndrome.
pubmed:affiliation
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural