Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1991-4-18
pubmed:abstractText
In one study, 6 cows with high erythrocyte potassium concentrations (HK cows) and 7 with low erythrocyte potassium concentrations (LK cows) were infused with 4.7% Na2EDTA solution intravenously for 4 h. The immediately observable clinical signs and the sequelae over a period of weeks were recorded and compared. There were no differences in the clinical responses of HK or LK cows to the infusion of Na2EDTA. In a second study, these clinical signs plus those produced experimentally by three other research groups were compared with both the clinical signs of milk fever recorded in three text books and those observed by one of the authors over a period of 25 years in dairy cattle practice. All of the clinical signs of milk fever occurred in the experimental model, but there were extra signs (excessive salivation, excessive lip and tongue actions, and tail lifting) which were not present or recorded in naturally occurring cases of hypocalcaemia. Hypocalcaemia induced in cows by the intravenous infusion of 4.7% Na2EDTA solution is a reasonably good model for the reproduction of the clinical signs of milk fever, but because of the extraneous signs, and the unusual nature of the subsequent deaths of 3 of 13 cows infused for 4 h, and the death of 1 of 2 cows infused for 4 h daily for 3 days, the model may not be a valid one for periods longer than 4 h in cows.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0514-7158
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
721-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
A comparison between the main clinical signs of milk fever in cows with those of hypocalcaemia induced by Na2EDTA solution.
pubmed:affiliation
Department of Physiology and Pharmacology, University of Queensland, St. Lucia, Australia.
pubmed:publicationType
Journal Article, Comparative Study