Linked Life Data

2127370

Source:http://linkedlifedata.com/resource/pubmed/id/2127370

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1991-4-17
pubmed:abstractText
In Escherichia coli, the superoxide dismutase genes (sodA and sodB) sense the availability of Fe through the action of the fur locus [E. C. Niederhoffer, C. M. Naranjo, K. L. Bradley, J. A. Fee (1990) Control of Escherichia coli superoxide dismutases (sodA and sodB) genes by the ferric uptake regulation (fur) locus, J. Bacteriol. 172, 1930-1938]. Previous work from other laboratories has shown that a variety of metal chelators and of redox-active aromatic compounds can dramatically induce expression of sodA. Here we show that non-redox-active, non-metal-chelating aromatic compounds also enhance expression of a chromosomal sodA gene fusion and that these effects are strongly modulated by the Fur phenotype (Fur +/-) and by the availability of iron in the culture medium. The compounds studied were ethidium bromide, hemin, 2,2'-bipyridine, 1,10-phenantroline, 4,7-phenantroline, rhodamine B1, rhodamine 6G, and, for comparison to previous studies, Paraquat.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0933-5854
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:geneSymbol
fur, sodA, sodB
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
237-41
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Novel effect of aromatic compounds on the iron-dependent expression of the Escherichia coli K12 manganese superoxide dismutase (sodA) gene.
pubmed:affiliation
Stable Isotope Resource, Los Alamos National Laboratory, NM 87545.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.