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pubmed-article:21266526pubmed:abstractTextDiffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of aggressive lymphomas with the activated B-cell-like subtype characterized by constitutive NF-?B activation. Activating mutations of CARD11 and inactivating mutations of A20 are frequent events in DLBCL. However, the full extent of genetic alterations in the NF-?B pathway regulators and their potential prognostic value in DLBCL remain to be investigated. We investigated the genetic abnormalities of CARD11, A20, and ABIN-1/2/3 (the A20 binding inhibitor of NF-?B) and their clinicopathologic correlation in gastrointestinal DLBCL.lld:pubmed
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pubmed-article:21266526pubmed:articleTitleA20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma.lld:pubmed
pubmed-article:21266526pubmed:affiliationDivision of Molecular Histopathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom.lld:pubmed
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