Source:http://linkedlifedata.com/resource/pubmed/id/21263290
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2011-2-14
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pubmed:abstractText |
Cartilage-based treatments have vast applications in plastic and reconstructive surgery, especially craniofacial constructs. Current techniques in craniofacial cartilage reconstructions greatly rely on autologous donor site harvest. Whole cartilage grafts are wrought with complications of warping, resorption, extrusion, and donor site morbidity. Percutaneous delivery of expanded chondrocytes would have the potential to expand a small quantity of autologous cells to deliver cell therapy. To deliver chondrocytes effectively, there must be a reliable medium in which chondrocytes can be kept. The purpose of this work is to highlight the utility of fibrin glue sealant, Evicel, as a suitable chondrocyte carrier in the treatment of a critical-sized defect model of nonarticular cartilage previously developed in our laboratory.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1536-3708
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
301-5
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pubmed:meshHeading |
pubmed-meshheading:21263290-Absorbable Implants,
pubmed-meshheading:21263290-Animals,
pubmed-meshheading:21263290-Biocompatible Materials,
pubmed-meshheading:21263290-Cartilage,
pubmed-meshheading:21263290-Cartilage, Articular,
pubmed-meshheading:21263290-Chondrocytes,
pubmed-meshheading:21263290-Disease Models, Animal,
pubmed-meshheading:21263290-Fibrin Tissue Adhesive,
pubmed-meshheading:21263290-Humans,
pubmed-meshheading:21263290-Rats,
pubmed-meshheading:21263290-Rats, Nude,
pubmed-meshheading:21263290-Tissue Engineering,
pubmed-meshheading:21263290-Xiphoid Bone
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pubmed:year |
2011
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pubmed:articleTitle |
Fibrin glue: a scaffold for cellular-based therapy in a critical-sized defect.
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pubmed:affiliation |
Division of Plastic and Reconstructive Surgery, Emory University, Atlanta, GA, USA.
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pubmed:publicationType |
Journal Article
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