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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-1-25
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pubmed:abstractText |
Hepatitis C virus (HCV) proteins activate the unfolded protein response (UPR) in experimental models. The role of the UPR in the pathogenesis of HCV-induced liver injury has not been determined. Our aim was to investigate the role of the UPR in the pathogenesis of chronic HCV.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ATF6 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Activating Transcription Factor 6,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DDIT3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/ERN1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Endoribonucleases,
http://linkedlifedata.com/resource/pubmed/chemical/Heat-Shock Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PERK kinase,
http://linkedlifedata.com/resource/pubmed/chemical/PPP1R15A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Phosphatase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor CHOP,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/eIF-2 Kinase,
http://linkedlifedata.com/resource/pubmed/chemical/molecular chaperone GRP78,
http://linkedlifedata.com/resource/pubmed/chemical/regulatory factor X transcription...
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1440-1746
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pubmed:author |
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pubmed:copyrightInfo |
© 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
319-27
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21261722-Activating Transcription Factor 6,
pubmed-meshheading:21261722-Adult,
pubmed-meshheading:21261722-Antigens, Differentiation,
pubmed-meshheading:21261722-Biopsy,
pubmed-meshheading:21261722-Case-Control Studies,
pubmed-meshheading:21261722-Cell Cycle Proteins,
pubmed-meshheading:21261722-Chi-Square Distribution,
pubmed-meshheading:21261722-DNA-Binding Proteins,
pubmed-meshheading:21261722-Endoribonucleases,
pubmed-meshheading:21261722-Female,
pubmed-meshheading:21261722-Gene Expression Regulation,
pubmed-meshheading:21261722-Heat-Shock Proteins,
pubmed-meshheading:21261722-Hepatitis C, Chronic,
pubmed-meshheading:21261722-Humans,
pubmed-meshheading:21261722-Immunohistochemistry,
pubmed-meshheading:21261722-Liver,
pubmed-meshheading:21261722-Male,
pubmed-meshheading:21261722-Protein Phosphatase 1,
pubmed-meshheading:21261722-Protein-Serine-Threonine Kinases,
pubmed-meshheading:21261722-Queensland,
pubmed-meshheading:21261722-RNA, Messenger,
pubmed-meshheading:21261722-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21261722-Transcription Factor CHOP,
pubmed-meshheading:21261722-Transcription Factors,
pubmed-meshheading:21261722-Unfolded Protein Response,
pubmed-meshheading:21261722-eIF-2 Kinase
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pubmed:year |
2011
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pubmed:articleTitle |
No evidence of the unfolded protein response in patients with chronic hepatitis C virus infection.
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pubmed:affiliation |
Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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