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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-5-11
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pubmed:abstractText |
External fistulas represent a disabling manifestation of Crohn's disease with a difficult curability and a high relapse rate despite a large therapeutic armamentarium. Stem cell therapy is a novel and promising approach for treatment of chronic inflammatory conditions. We therefore investigated the feasibility, safety and efficacy of serial intrafistular injections of autologous bone marrow-derived mesenchymal stromal cells (MSCs) in the treatment of fistulising Crohn's disease.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1468-3288
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pubmed:author |
pubmed-author:AlvisiCostanzaC,
pubmed-author:AvanziniMaria AntoniettaMA,
pubmed-author:BernardoMaria EsterME,
pubmed-author:CalliadaFabrizioF,
pubmed-author:CiccocioppoRacheleR,
pubmed-author:CorazzaGino RobertoGR,
pubmed-author:DionigiPaoloP,
pubmed-author:LocatelliFrancoF,
pubmed-author:MaccarioRitaR,
pubmed-author:MinelliAntonellaA,
pubmed-author:PerottiCesareC,
pubmed-author:SgarellaAdeleA,
pubmed-author:UbezioCristinaC,
pubmed-author:VanoliAlessandroA
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pubmed:issnType |
Electronic
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
788-98
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pubmed:meshHeading |
pubmed-meshheading:21257987-Adolescent,
pubmed-meshheading:21257987-Adult,
pubmed-meshheading:21257987-Anus Diseases,
pubmed-meshheading:21257987-Apoptosis,
pubmed-meshheading:21257987-Coculture Techniques,
pubmed-meshheading:21257987-Crohn Disease,
pubmed-meshheading:21257987-Cytokines,
pubmed-meshheading:21257987-Feasibility Studies,
pubmed-meshheading:21257987-Female,
pubmed-meshheading:21257987-Humans,
pubmed-meshheading:21257987-Immunity, Mucosal,
pubmed-meshheading:21257987-Immunophenotyping,
pubmed-meshheading:21257987-Magnetic Resonance Imaging,
pubmed-meshheading:21257987-Male,
pubmed-meshheading:21257987-Mesenchymal Stem Cell Transplantation,
pubmed-meshheading:21257987-Mesenchymal Stem Cells,
pubmed-meshheading:21257987-Rectal Fistula,
pubmed-meshheading:21257987-T-Lymphocytes, Regulatory,
pubmed-meshheading:21257987-Treatment Outcome,
pubmed-meshheading:21257987-Wound Healing,
pubmed-meshheading:21257987-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease.
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pubmed:affiliation |
Clinica Medica I, Fondazione IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Pavia, Italy. rachele.ciccocioppo@unipv.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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