Linked Life Data

21257761

Source:http://linkedlifedata.com/resource/pubmed/id/21257761

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2011-4-1
pubmed:abstractText
Titin, the largest protein in the human body, is well known as a molecular spring in muscle cells and scaffold protein aiding myofibrillar assembly. However, recent evidence has established another important role for titin: that of a regulatory node integrating, and perhaps coordinating, diverse signaling pathways, particularly in cardiomyocytes. We review key findings within this emerging field, including those related to phosphorylation of the titin springs, and also discuss how titin participates in hypertrophic gene regulation and protein quality control.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1083-351X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
25
pubmed:volume
286
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9905-12
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
The giant protein titin: a regulatory node that integrates myocyte signaling pathways.
pubmed:affiliation
Department of Cardiovascular Physiology, Ruhr University Bochum, D-44780 Bochum, Germany. martina.krueger@rub.de
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't