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pubmed-article:21256242pubmed:abstractTextType I IFNs (IFN?/?) are essential anti-viral cytokines produced in response to the detection of viral components by host pattern recognition receptors. IFN?/? production is transient, and aberrant activation can be hazardous to the host. In this article, we review our current understanding of host negative regulatory mechanisms that control IFN?/? production.lld:pubmed
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pubmed-article:21256242pubmed:copyrightInfoCopyright © 2011 Institut Pasteur. Published by Elsevier SAS. All rights reserved.lld:pubmed
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pubmed-article:21256242pubmed:articleTitlePutting the brakes on the anti-viral response: negative regulators of type I interferon (IFN) production.lld:pubmed
pubmed-article:21256242pubmed:affiliationInstitute of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.lld:pubmed
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