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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-3-14
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pubmed:abstractText |
Type I IFNs (IFN?/?) are essential anti-viral cytokines produced in response to the detection of viral components by host pattern recognition receptors. IFN?/? production is transient, and aberrant activation can be hazardous to the host. In this article, we review our current understanding of host negative regulatory mechanisms that control IFN?/? production.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1769-714X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 Institut Pasteur. Published by Elsevier SAS. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
291-302
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pubmed:meshHeading |
pubmed-meshheading:21256242-Animals,
pubmed-meshheading:21256242-Cytoplasm,
pubmed-meshheading:21256242-Host-Pathogen Interactions,
pubmed-meshheading:21256242-Humans,
pubmed-meshheading:21256242-Immunity, Innate,
pubmed-meshheading:21256242-Immunomodulation,
pubmed-meshheading:21256242-Interferon Regulatory Factors,
pubmed-meshheading:21256242-Interferon Type I,
pubmed-meshheading:21256242-Protein-Serine-Threonine Kinases,
pubmed-meshheading:21256242-RNA, Viral,
pubmed-meshheading:21256242-Signal Transduction,
pubmed-meshheading:21256242-Toll-Like Receptors,
pubmed-meshheading:21256242-Virus Diseases,
pubmed-meshheading:21256242-Viruses
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pubmed:year |
2011
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pubmed:articleTitle |
Putting the brakes on the anti-viral response: negative regulators of type I interferon (IFN) production.
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pubmed:affiliation |
Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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