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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1991-2-19
|
| pubmed:abstractText |
Histopathologic studies and isolation of virus and bacteria in culture were carried out for 71 children less than 5 years of age with fatal pneumonia. A potential microbial etiology was identified for 61 children (86%): bacteria for 19 (27%), virus for 16 (23%), and virus plus bacteria for 26 (37%). Staphylococcus was the most prevalent pathogen, alone or in combination with other organisms, followed by Pseudomonas aeruginosa. Viral infection may predispose to bacterial infection in some children. A correlation of clinical course, results of cultures, and morphologic changes revealed cofactors that may have contributed to a fatal outcome. Lung abscess, pericarditis, myocarditis, endocarditis, and meningitis were associated with bacterial infection. Many patients in this study had severe bronchopneumonia, with a high prevalence of complications such as abscess (62%), atelectasis (40%), pericarditis (28%), and empyema (7%). Such complications added to multiple infections, measles, and malnutrition contributed to the fatal outcome in these children.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0162-0886
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
12 Suppl 8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
S1055-64
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2125358-Age Factors,
pubmed-meshheading:2125358-Airway Obstruction,
pubmed-meshheading:2125358-Bacterial Infections,
pubmed-meshheading:2125358-Bronchi,
pubmed-meshheading:2125358-Child, Preschool,
pubmed-meshheading:2125358-Female,
pubmed-meshheading:2125358-Humans,
pubmed-meshheading:2125358-Infant,
pubmed-meshheading:2125358-Infant, Newborn,
pubmed-meshheading:2125358-Lung,
pubmed-meshheading:2125358-Lung Abscess,
pubmed-meshheading:2125358-Male,
pubmed-meshheading:2125358-Metaplasia,
pubmed-meshheading:2125358-Necrosis,
pubmed-meshheading:2125358-Pleural Effusion,
pubmed-meshheading:2125358-Pneumonia,
pubmed-meshheading:2125358-Pseudomonas Infections,
pubmed-meshheading:2125358-Pseudomonas aeruginosa,
pubmed-meshheading:2125358-Sepsis,
pubmed-meshheading:2125358-Staphylococcal Infections,
pubmed-meshheading:2125358-Virus Diseases
|
| pubmed:articleTitle |
Etiology of infection and morphologic changes in the lungs of Filipino children who die of pneumonia.
|
| pubmed:affiliation |
Research Institute for Tropical Medicine, Department of Health, Manila, Philippines.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|