|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2011-3-3
|
|
pubmed:abstractText |
The incidence of and risk factors for community-acquired pneumonia (CAP) are described from 2000 to 2005 in a multicenter US cohort of HIV-infected children. In 736 patients, 87 episodes of CAP (33.2 events/1000 person-years) had a mean CD4% of 23% (controls: 30%) and mean CD4 cell count of 668 cells/?l (controls: 870 cells/?l). CAP incidence decreased 44% from 2000-2001 to 2002-2005. On multivariate analysis, viral load at least 100 000 copies/ml (odds ratio 3.98; confidence interval 1.05-15.13) was associated with CAP. Herd immunity through pneumococcal immunization may have diluted the effect of individual immunization in this cohort.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1473-5571
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
13
|
|
pubmed:volume |
25
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
717-20
|
|
pubmed:meshHeading |
pubmed-meshheading:21252630-Adolescent,
pubmed-meshheading:21252630-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:21252630-CD4 Lymphocyte Count,
pubmed-meshheading:21252630-Child,
pubmed-meshheading:21252630-Child, Preschool,
pubmed-meshheading:21252630-Community-Acquired Infections,
pubmed-meshheading:21252630-Female,
pubmed-meshheading:21252630-HIV Infections,
pubmed-meshheading:21252630-Humans,
pubmed-meshheading:21252630-Incidence,
pubmed-meshheading:21252630-Infant,
pubmed-meshheading:21252630-Infant, Newborn,
pubmed-meshheading:21252630-Male,
pubmed-meshheading:21252630-Pneumonia,
pubmed-meshheading:21252630-Risk Factors,
pubmed-meshheading:21252630-Viral Load,
pubmed-meshheading:21252630-Young Adult
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Incidence of and risk factors for community acquired pneumonia in US HIV-infected children, 2000-2005.
|
|
pubmed:affiliation |
Department of Pediatrics, Children's Hospital Philadelphia, Pennsylvania, USA. steenhoff@e-mail.chop.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
